Undergraduate Program in
Biology and Medicine

DEPARTMENT OF BIOLOGY at the UNIVERSITY OF ROCHESTER
scanline

  Biology Course Descriptions

Course No.

Course Title

Description

BIO 104K

Ecosystem Conservation and Human Society

As the natural resources on which human society depends are depleted, the need for sound conservation policies increases. The course examines a new approach in conservation biology that identifies and places economic value on the services that natural ecosystems provide. Such services are basic to sustainable societies and include clean water and air, waste decomposition, pollination and farm land productivity. Major themes the course covers include an overview of other approaches in conservation biology, a review of the services that ecosystems provide, ways the value of these services are determined, and how this novel approach is influencing economic and political policy at local, national, and international levels.

BIO 110

Principles of Biology I

The first semester in a year long course sequence designed for majors and minors biochemistry, molecular and cellular evolution, cell reproduction, fundamentals of genetics and molecular biology

BIO 111

Principles of Biology II

The second semester of the introductory sequence designed for majors in biology. Topics include: Evolution (natural selection, speciation, plant and animal diversity), Biodiversity, Plant and animal physiology, Ecology (population genetics, ecosystem structure, species interactions).
Concurrent enrollment is BIO 111P is not required, but is strongly recommended for current or prospective Biology majors, as either 111P or 113P is required for Biology majors. The laboratory course is also recommended for those intending to apply to medical school.

BIO 111P

Introductory Biology Laboratory

This is the lab course which accompanies the lecture course Principles of Biology II. The content of the course is drawn from the lecture material. Topics include plant and animal diversity, anatomical dissections, methods in bacteriology, animal behavior, and basic physiology. An emphasis is placed on problem solving, critical thinking and experimental design.
While this course is designed to accompany BIO 111, students taking BIO 111 are not required to register concurrently for BIO 111P. BIO 111P is strongly recommended for current or prospective Biology majors, as either 111P or 113P is required for Biology majors. Either of these lab courses is also recommended for those intending to apply to medical school. Biomedical engineering majors consult with their advisors about whether to take this course.

BIO 112

Perspectives in Biology I

The first semester of a two-course introductory sequence for students with a strong background in science. Topics include biochemistry, molecular and cellular evolution, cell reproduction, fundamentals of genetics and molecular biology. This course differs from BIO 110: there will be greater emphasis on the chemistry underlying biological processes and on experimental approaches, data analysis, and quantitative methods. It will also include reading original papers, and a significant writing component (e.g. preparation of a book review from among selected titles, such as The Selfish Gene). Note both BIO 110 and BIO 112 are designed to prepare students who intend to major in biology.
Prerequisites: Students with a score of 4 or 5 on the AP Biology test, particularly those who have an interest in research. Completion or concurrent enrollment in CHM 131 or equivalent.

BIO 113

Perspectives in Biology II

Second semester of a two-course introductory sequence for students with a strong background and interest in science. Topics include: evolution, organismal diversity, ecology, and functional biology. This course differs from BIO 111 in that there will be greater emphasis on experimental approaches, data analysis, and quantitative methods, and will include reading original papers. Note both BIO 110 and BIO 112 are designed to prepare students who intend to major in biology. Open only to freshman prospective majors or by permission of instructor.
Concurrent enrollment in BIO 113P is not required, but is strongly recommended for current or prospective Biology majors, as either 111P or 113P is required for Biology majors. The laboratory course is also recommended for those intending to apply to medical school.

BIO 113P

Perspectives in Biology Lab

This is the laboratory course which accompanies the lecture course Perspectives in Biology II. Course content is drawn from the lecture material and includes biological diversity, ecology, evolution, animal behavior, physiology and bioinformatics. Emphasis is placed on problem solving, critical thinking, experimental design and data analysis.
While this course is designed to accompany BIO 113, students taking BIO 113 are not required to register concurrently for BIO 113P. BIO 113P is strongly recommended for current or prospective Biology majors, as either 111P or 113P is required for Biology majors. Either of these lab courses is also recommended for those intending to apply to medical school. Biomedical engineering majors consult with their advisors about whether to take this course.

BIO 151

Introduction to Biochemistry - Lab

The course is designed to introduce sophomore biology majors to experimental approaches in biochemistry, including enzyme assays, protein analysis, and the use of antibodies. Students will also develop light microscopic skills, e.g. , using fluorescent dyes in organelle isolation. The laboratory emphasizes experimental design and data analysis and complements BIO 250, Biochemistry. This course can be used to satisfy a ½ laboratory requirement in the BA and other UPBM tracks.

BIO 198

Principles of Genetics

Methods of genetic analysis are stressed. Topics include: Mendelian assortment; gene interaction; linkage and mapping; methods of genetic analysis in yeast, bacteria and phage; DNA replication, recombination, repair and mutation; gene expression and its regulation; transposons and retroviruses; recombinant DNA technologies; cancer as a genetic disease.

BIO 198P

Principles of Genetics Lab

This course is an introduction to basic genetic theory and laboratory practices. Topics include classical inheritance in eukaryotes, bacterial genetics and molecular technology techniques. Emphasis is on data analysis and experimental design.

BIO 201

Lectures in Physiology

Function of various mammalian systems with special emphasis on humans. Topics include: excitable tissue, respiration, nutrition, reproduction, endocrinology, skeletal, circulatory and renal systems; homeostatic mechanism. Students will attend lecture and take examinations with students in BIO 204, Mammalian Physiology, and attend one hour of mandatory recitation per week. Laboratory exercises will not be conducted.

BIO 202

Molecular Biology

This course deals with the molecular mechanisms of gene replication, gene expression, and the control of gene expression in both prokaryotic and eukaryotic cells. Topics include: enzymatic mechanisms of DNA replication, recombination and repair; transposable elements; DNA transcription; RNA splicing; RNA translation; repressors, activators and attenuators; recombinant DNA and genetic engineering.

BIO 203

Mammalian Anatomy

This course deals with the structural and systematic anatomy of animals with special emphasis on human beings. Laboratory includes the dissection of fresh and preserved tissue plus analysis of structures and systems.

BIO 204

Mammalian Physiology

Function of various mammalian systems with special emphasis on humans. Topics include: excitable tissue; respiration; nutrition; reproduction; endocrinology; skeletal, circulatory and renal systems; homeostatic mechanisms.

BIO 205

Evolution

Fundamentals of Evolution. Topics include natural selection and its ecological basis, population genetics including selection and drift, speciation, and molecular evolution including the neutral theory, molecular phylogeny and the molecular clock.

BIO 210

Molecular Cell Biology

An intermediate level course that covers fundamental cell processes at the molecular level. Topics include organelle structure and functions, membrane biogenesis, cytoskeleton, cell signaling, cell cycle growth and death.

BIO 215

Molecular Biology of Cell Signalling

This course offers an introduction to cell signalling. We will explore basic molecular mechanisms of signal transduction, and study how these mechanisms are used in different contexts to direct cell fate during development, physiology and disease. The course will draw heavily on experiments from the classic and most recent primary literature.

BIO 220

Advanced Cell Biology

An advanced course focusing on a mechanistic understanding of cellular organization and function. This course relies heavily on the primary research literature, classic and recent, and the design and interpretation of experiments, drawn from biochemistry, microscopy and genetics. Topics include the cytoskeleton, membrane traffic, cell-cell signaling and the cell cycle. Active participation in classroom discussions is an essential feature of the course.

BIO 222

Biology of Aging

This course focuses on molecular mechanisms of aging. We will discuss popular theories of aging, model organisms used in aging research, evolution of aging, relation between aging and cancer, human progeroid syndromes, and interventions to slow aging.

BIO 225

Laboratory in Ecology & Evolutionary Biology

This course emphasizes the development of testable questions and implementation of appropriate observations and experiments on a series of topics in ecology and evolution. Many of the mini-studies will be done in the field on non-model organisms native to New York. Students will gain experience on field and lab methods used in ecology and evolutionary biology (including relevant computer applications), critiquing published scientific studies, writing scientific reports, and presentation of scientific results.

BIO 226

Developmental Biology

This course deals with the cellular and molecular aspects of animal development, with emphasis on processes and underlying mechanisms. Topics include embryonic cleavage, gastrulation, early development of model vertebrates and invertebrates, patterning of cell fates along embryonic axes of Drosophila and vertebrates, organogenesis and stem cells.

BIO 243

Eukaryotic Gene Regulation

This advanced course examines mechanisms of transcription initiation, eukaryotic chromosome structure and its modifications, mechanisms of chromatin-mediated regulation of gene expression, as well as epigenetics and functional genomics. Lectures and readings draw heavily on primary literature both classic and most recent. IND 443 and BIO 443 students are required to give a 30 minute presentation on a selected topic.

BIO 247

Environmental Animal Physiology

This course is designed for sophomore biology majors who want to deepen their understanding of animal function by examining how animals cope with environmental challenges. This includes cellular and physiological adaptations to extremes of temperature, salinity, and altitude. This course can be used to satisfy an upper level elective/diversity requirement in all UPBM tracks and as a "group" A requirement in the BA track.

BIO 250

Introduction to Biochemistry

Biochemistry 250 will cover fundamental aspects of biochemistry, including bioenergetics, protein structure, kinetic analysis of enzyme action, and general intermediary metabolism. The text will be the 5th edition of Lehninger's "Principles of Biochemistry" by Nelson and Cox, with its accompanying Web site, which includes access to CHIME tutorials that explore structure- function relationships in biomolecules.

BIO 253

Computational Biology

An introduction to the history, theory, and practice of using computers to conduct biological research. Topics include the fundamentals of Linux-based computing and perl programming, accessing and storing biological data, alignment of molecular sequences, and computer-based analysis of data.

BIO 260

Animal Behavior

Examines animal behavior from an ecological and evolutionary perspective. Topics include social organization, mating systems, foraging, aggression, and animal learning. Students also learn quantitative techniques in behavioral biology.

BIO 263

Ecology

A survey of adaptations to the physical environment, dynamics of natural populations, interactions between species, and human impact on the environment.

BIO 265

Molecular Evolution

This course explores evolution at the molecular level. We will use basic evolutionary principles to infer history from DNA sequences; to determine what forces have shaped the evolution of genes and genomes; to understand the relationship between molecular evolution and phenotypic evolution; and to address applied problems, like assigning biological function to genome sequences, finding the sources of epidemics, and finding the genes involved in human disease.

BIO 268

Laboratory in Molecular, Cell and Developmental Biology

This course is designed to provide (1) introduction to model organisms (2) training in specific methods used in molecular, cell and developmental biology research, with emphasis on data acquisition and analysis (3) experience in the design and execution of experiments, reading and writing scientific reports, and public scientific presentation.

BIO 420

Advanced Cell Biology

An advanced course focusing on a mechanistic understanding of cellular organization and function. This course relies heavily on the primary research literature, classic and recent, and the design and interpretation of experiments, drawn from biochemistry, microscopy and genetics. Topics include the cytoskeleton, membrane traffic, cell-cell signaling and the cell cycle. Oral and written student presentations and active participation in classroom discussions are essential features of the course.

BIO 422

Biology of Aging

This course focuses on molecular mechanisms of aging. We will discuss popular theories of aging, model organisms used in aging research, evolution of aging, relation between aging and cancer, human progeroid syndromes, and interventions to slow aging.

BIO 443

Eukaryotic Gene Regulation

This advanced course examines mechanisms of transcription initiation, eukaryotic chromosome structure and its modifications, mechanisms of chromatin-mediated regulation of gene expression, as well as epigenetics and functional genomics. Lectures and readings draw heavily on primary literature both classic and most recent. IND 443 and BIO 443 students are required to give a 30 minute presentation on a selected topic.

BIO 465

Molecular Evolution

This course explores evolution at the molecular level. We use evolutionary principles to infer history from DNA sequences, to determine what forces have shaped the evolution of genes and genomes, to understand the relationship between molecular evolution and phenotypic evolution, and to address applied problems, like assigning biological function to genome sequences, finding the sources of epidemics, and finding the genes involved in human diseases.

BIO 468

Laboratory in Molecular, Cell and Developmental Biology

A series of experiments, each lasting two or three weeks, introducing various organisms and techniques. Emphasizes (1) data acquisition and analysis (2) experience in the design and execution of experiments, writing scientific reports, and public scientific presentation.

BIO 47x

Advanced Evolutionary Genetics Topics

One of a four-course sequence that provides comprehensive coverage of advanced topics in ecology and evolutionary biology. Areas covered include: population and community ecology; population and quantitative genetics; molecular evolution; evolutionary genomics; evo-devo; phylogenetics; and speciation. This course is intended for graduate students; exceptional undergraduate students can enroll by permission of the course coordinator.

BIO 516

Cell/Dev/Mol Biology Seminar

This one credit course examines current topics in cell, developmental and molecular biology. Student-led seminars and discussions based on representative publications in the recent literature. One or several broad topics, drawn from active fields of cell, developmental and molecular biology, will be covered each semester.

BIO 580

Journal Club in Ecology and Evolution

Current topics in ecology and evolutionary biology are explored by reading research and review papers. Students choose topics for reading and lead discussions of their chosen topics. This course carries one credit.

BIO 584

Seminar in Evolution

Biology Colloquium. Members of the staff and advanced students in the biological sciences meet on regularly announced dates for presentation and discussion of research by members of the department or invited guests. These seminars are open to all.