Positions

A postdoctoral position is available in the Welte laboratory at the University of Rochester. We investigate how microtubule-based organelle transport is regulated during development, in particular how cells control specificity, timing and destination of transport. Our research employs a unique model system, lipid droplets in Drosophila embryos. This model system can be analyzed by a combination of genetics, biophysics, live imaging and biochemistry. For an example of this powerful approach, see our recent paper in Cell. We are looking for an energetic individual with a cell-biology and/or Drosophila background to characterize the molecular mechanism of the novel protein Halo. Halo is a master regulator of droplet motion and controls both timing and directionality of transport. As Halo targets to lipid droplets and physically interacts with microtubule motors, it likely directly modulates the droplet transport machinery. To apply, please contact Dr. Michael Welte (michael.welte@rochester.edu).