Venture-Ready Technologies

Venture-Ready Technologies are some of the University of Rochester’s most promising inventions. We believe the technologies and innovations described below have significant commercial potential. Some of these items could fit nicely into a company’s existing intellectual property portfolio to enhance a product line or help launch a new one. Others represent platform technologies that could constitute the foundation of a new startup company. In either case, we invite you to peruse the following which will be updated periodically with new featured patents. If anything is of interest, please contact UR Ventures.


Protease Activated Cytokines as Anti-Cancer Therapy

A novel therapy method for delivering localized anti-cancer responses without adverse body-wide side effects.


Light-Controlled Immunotherapy

A novel therapy using light-activated chemokine receptors to direct specific lymphocytes to desired locations within a patient’s body.


Isotope-Labeled acyl-CoA

A novel protocol to produce large quantities of nearly 100% homogenous heavy-labeled acyl-CoAs rapidly and inexpensively.


Novel Small Molecules to Treat Alzheimer’s Disease

Small compounds that inhibit the uptake of amyloid-β into the brain.


Novel Cell Therapy for Treating CNS Injury

A new cell therapy for treating damage to the central nervous system.


Treatment for Hyperammonemic Encephalopathy and Seizures

A treatment for hyperammonemic Encephalopathy and Seizures.


Treating and Monitoring Rheumatoid Arthritis with PDE5 Inhibitors

A safe and effective treatment for Rheumatoid Arthritis using approved drugs.


A Novel Method to Predict the Outcome of Chronic Lymphocytic Leukemia

A simple and robust in vitro DNA-based diagnostic assay to aid in determining the prognosis of patients with chronic lymphocytic leukemia (CLL).


Improved Safer Nasal Spray Flu Vaccines

A safer and more effective nasal vaccine against influenza.


Development of Arenavirus Vaccines through Codon Deoptimization

A novel strategy for developing safe and effective live-attenuated arenavirus vaccines.


Modulating Melanin Expression

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Compounds that can induce melanin expression to aid in certain clinical indications or for cosmetic purposes.



Protecting, Repairing, and Regenerating Articular Cartilage and Fibrocartilaginous Tissues

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Methods for the protection, repair, and regeneration of articular cartilage and fibrocartilaginous tissues using recombinant parathyroid hormones.


Treatment for Genetic Diseases through Correction of pre-mRNA Splicing

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An RNA therapeutic approach based on a “tailor-made” mRNA splice factor to treat genetic diseases that are caused by mRNA splice site mutations, such as muscular dystrophy, β-thalassemia, retinitis pigmentosa, neurofibromatosis, and cancers.


Dog Flu Vaccine

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A live-attenuated vaccine for canine influenza virus.


A Vaccine Against Type 1 Diabetes


A novel vaccine against Type I Diabetes


A New Biomarker to Predict Patient Response to Anti-TNF Therapy


A biomarker to save time and money in the treatment of arthritis.


A Therapeutic Approach to Replace or Improve Deep Brain Stimulation


A method to enhance the effects of deep brain stimulation.

Peptide Therapy for Inflammatory Bowel and Celiac Diseases

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A safe and effective therapy based on the bacterial AvrA peptide for the treatment of inflammatory bowel and celiac diseases.


Tetravalent Dengue Fever Vaccine


A vaccine effective against all four strains of the Dengue virus.


RNA Therapeutics for Diseases Caused by Nonsense Mutations


A method to suppress premature stop codons in order to generate full-length mRNA using target-specific guide mRNAs.


Novel Anti-Obesity Therapy


A protein/peptide-based therapy for the prevention and treatment of obesity with desirable side effect profile.


A Method of Remyelinating Congenitally Dysmyelinated Forebrains


A method of remyelinating axons using oligodendrocyte progenitor cells.


Novel Preventative Anti-caries and Periodontal Diseases Treatment


A novel method for treating and preventing dental diseases.


Novel Lung Surfactant Peptides


A novel synthetic lung surfactant for the treatment of neonatal and acute respiratory distress syndromes.


Methods to Inhibit the Progression of Follicular Lymphoma


Methods for obtaining specific and non-toxic inhibitors of Activation Induced Deaminase nuclear import that prevent the progression of follicular lymphoma, once diagnosed.

Human Biliverdin Reductase Peptide for the Treatment of Diabetes

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A human Biliverdin Reductase-based peptide therapy for the treatment of diabetes.


Novel Method to Prevent or Treat Fibrosis

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A novel method for treating and preventing fibrosis and fibrosis-related conditions using fibronectin binding proteins and polypeptides.