{"id":7956,"date":"2012-11-12T16:34:35","date_gmt":"2012-11-12T16:34:35","guid":{"rendered":"http:\/\/www.rochester.edu\/newscenter\/?p=7956"},"modified":"2020-05-07T12:42:36","modified_gmt":"2020-05-07T16:42:36","slug":"super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices","status":"publish","type":"post","link":"https:\/\/www.rochester.edu\/newscenter\/super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices\/","title":{"rendered":"Diagnostic Devices to Feature Super-Thin Filters"},"content":{"rendered":"<p><em>NSF Grant to Support University-Business Partnership<\/em><\/p>\n<p>Nano-porous silicon membranes developed at the University of Rochester&#8217;s Hajim School of Engineering and Applied Sciences will soon be used to manufacture portable devices that can analyze DNA in remote settings.<\/p>\n<p>A $600,000 grant from the National Science Foundation will fund a partnership among Associate Professor of Biomedical Engineering James McGrath, SiMPore, Rochester Institute of Technology, and Integrated Nanotechnologies (INT) to fabricate the devices.<\/p>\n<figure id=\"attachment_7966\" aria-describedby=\"caption-attachment-7966\" style=\"width: 275px\" class=\"wp-caption alignleft\"><a href=\"https:\/\/www.rochester.edu\/newscenter\/wp-content\/uploads\/2012\/11\/PastedGraphic-11.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-7966\" title=\"wafer\" src=\"https:\/\/www.rochester.edu\/newscenter\/wp-content\/uploads\/2012\/11\/PastedGraphic-11.jpg\" alt=\"large metal disk\" width=\"275\" height=\"206\" \/><\/a><figcaption id=\"caption-attachment-7966\" class=\"wp-caption-text\">4&#8243; wafer with 160 membranes.<br \/>(Photo by SiMPore Inc.)<\/figcaption><\/figure>\n<p>A key component will be filters made of the super-thin silicon membranes. The filters being used today are sponge-like and about 1,000 times thicker than the nanomembranes.<\/p>\n<p>&#8220;The thicker the membrane, the less efficiently they work as a filter,&#8221; said McGrath, who helped invent the super-thin membranes. &#8220;Our membranes are one-molecule thick with tiny holes capable of quickly separating particles close in size.&#8221;<\/p>\n<p>The super-thin filters are manufactured by<a href=\"http:\/\/www.simpore.com\/\">SiMPore<\/a>, a University-based start-up company founded by McGrath and colleagues. McGrath&#8217;s team is working to integrate the filters into INT&#8217;s components to create the highly portable, chip-based devices.<\/p>\n<p>At present, pathogen-testing is done by machines that are about the size of an office printer, but the collaborators hope to create microchip-sized versions the device as part of the grant effort. Such a tiny device could be inexpensive and taken into the field for military use and for third world medicine.<\/p>\n<p>McGrath sees the University\/industry grant as part of a growing trend. &#8220;The National Science Foundation and other federal funding groups want to support public-private partnerships that can energize the economy and create jobs,&#8221; he said.<\/p>\n<p><a href=\"http:\/\/www.integratednano.com\/index.aspx\">Integrated Nano-Technologies<\/a>\u00a0is a high-tech firm in the Rochester area that develops systems for detecting and identifying small quantities of biological materials.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>DNA analysis and pathogen testing relies on filtration.  These new membrane filters will be about 1,000 times thinner than the sponge-like filters used now, lending themselves to yet smaller, portable instrumentation for use in the field. <\/p>\n","protected":false},"author":16,"featured_media":7976,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[116],"tags":[18742,2306,18632,19182,37312,6106,37822],"class_list":["post-7956","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sci-tech","tag-department-of-biomedical-engineering","tag-grant","tag-hajim-school-of-engineering-and-applied-sciences","tag-james-mcgrath","tag-materials-science-program","tag-national-science-foundation","tag-urnano"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Diagnostic Devices to Feature Super-Thin Filters<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.rochester.edu\/newscenter\/super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Diagnostic Devices to Feature Super-Thin Filters\" \/>\n<meta property=\"og:description\" content=\"DNA analysis and pathogen testing relies on filtration. These new membrane filters will be about 1,000 times thinner than the sponge-like filters used now, lending themselves to yet smaller, portable instrumentation for use in the field.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.rochester.edu\/newscenter\/super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices\/\" \/>\n<meta property=\"og:site_name\" content=\"News Center\" \/>\n<meta property=\"article:published_time\" content=\"2012-11-12T16:34:35+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-05-07T16:42:36+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.rochester.edu\/newscenter\/wp-content\/uploads\/2012\/11\/nano-membrane_sorting.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"600\" \/>\n\t<meta property=\"og:image:height\" content=\"467\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Peter Iglinski\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@PiDaddy\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Peter Iglinski\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices\\\/\"},\"author\":{\"name\":\"Peter Iglinski\",\"@id\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/#\\\/schema\\\/person\\\/f7a217a901be900507c6e137448f5d5a\"},\"headline\":\"Diagnostic Devices to Feature Super-Thin Filters\",\"datePublished\":\"2012-11-12T16:34:35+00:00\",\"dateModified\":\"2020-05-07T16:42:36+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices\\\/\"},\"wordCount\":297,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/wp-content\\\/uploads\\\/2012\\\/11\\\/nano-membrane_sorting.jpg\",\"keywords\":[\"Department of Biomedical Engineering\",\"grant\",\"Hajim School of Engineering and Applied Sciences\",\"James McGrath\",\"Materials Science Program\",\"National Science Foundation\",\"URnano\"],\"articleSection\":[\"Science &amp; Technology\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices\\\/\",\"url\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices\\\/\",\"name\":\"Diagnostic Devices to Feature Super-Thin Filters\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/wp-content\\\/uploads\\\/2012\\\/11\\\/nano-membrane_sorting.jpg\",\"datePublished\":\"2012-11-12T16:34:35+00:00\",\"dateModified\":\"2020-05-07T16:42:36+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/#\\\/schema\\\/person\\\/f7a217a901be900507c6e137448f5d5a\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/super-thin-membranes-used-in-lab-on-a-chip-diagnostic-devices\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/wp-content\\\/uploads\\\/2012\\\/11\\\/nano-membrane_sorting.jpg\",\"contentUrl\":\"https:\\\/\\\/www.rochester.edu\\\/newscenter\\\/wp-content\\\/uploads\\\/2012\\\/11\\\/nano-membrane_sorting.jpg\",\"width\":600,\"height\":467,\"caption\":\"Artist's rendering of molecules being sorted by the membrane. 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