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Posts Tagged Andrei Seluanov

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Close up of a degu (small Chilean rodent) seen in shadow and perched on a branch.
Science & Technology
October 16, 2024 | 08:17 am

Comparing gene sequences across species to understand aging and dementia

A new grant partners longevity researchers and Alzheimer’s experts at Rochester to study the gene mechanisms that contribute to long and healthy lifespans.

topics: Andrei Seluanov, Department of Biology, Hongbo Liu, M. Kerry O'Banion, Medical Center, research funding, School of Arts and Sciences, Vera Gorbunova,
naked mole rat against a black background. The successful transfer of a naked mole rat's gene that produces HMW-HA to a mouse extends the mouse's lifespan.
Science & Technology
August 23, 2023 | 11:02 am

Longevity gene from naked mole rats extends lifespan of mice

The successful gene transfer paves the way for improving the health and lifespan of humans, too.

topics: Andrei Seluanov, Department of Biology, featured-post-side, Medical Center, research finding, School of Arts and Sciences, Vera Gorbunova,
young woman holds photo of an older woman's eyes in front of her face to illustrate gene regulation.
Science & Technology
May 26, 2022 | 10:50 am

Gene regulation may hold clue to longer life

Rochester biologists who study the genetics of lifespan suggest new targets to combat aging and age-related diseases.

topics: Andrei Seluanov, Department of Biology, featured-post-side, longevity, research finding, School of Arts and Sciences, Vera Gorbunova,
Gorbunova and Seluanov standing next to each other in lab, looking at camera.
Science & Technology
March 16, 2022 | 12:29 pm

Connecting the dots between aging, Alzheimer’s, and ‘junk DNA’

Biologists Vera Gorbunova and Andrei Seluanov join colleagues at Brown and NYU in the quest to find potential targets of treatments and therapeutics for neurodegenerative diseases.

topics: Andrei Seluanov, Department of Biology, National Institutes of Health, research funding, School of Arts and Sciences, Vera Gorbunova,
box filled with rusty tools and other junk
Science & Technology
October 20, 2021 | 08:35 am

Is ‘junk DNA’ a key to killing cancer cells?

Rochester biologists show how a selfish genetic element called retrotransposons that can cause tumors may also trigger the death of cancer cells.

topics: Andrei Seluanov, cancer, Department of Biology, featured-post, research finding, School of Arts and Sciences, Vera Gorbunova, Yang Zhao,
at in flight against blue sky.
Science & Technology
July 8, 2020 | 12:37 pm

Bats offer clues to treating COVID-19

Bats carry many viruses, including the one behind COVID-19, without becoming ill. University of Rochester biologists are studying the immune system of bats to find potential ways to “mimic” that system in humans.

topics: Aging, Andrei Seluanov, COVID-19, Department of Biology, featured-post-side, School of Arts and Sciences, Vera Gorbunova,
older woman in a swimsuit and cap flexing her muscles at the beach.
Science & Technology
April 19, 2019 | 10:15 am

‘Longevity gene’ responsible for more efficient DNA repair

Rochester researchers have uncovered more evidence that the key to the “Fountain of Youth” may reside in a gene that is found to produce more potent proteins in species with longer lifespans.

topics: Andrei Seluanov, Department of Biology, Department of Biomedical Genetics, Dirk Bohmann, longevity, Medical Center, research finding, School of Arts and Sciences, Vera Gorbunova,
aging hands gripping a cane.
Science & Technology
March 14, 2019 | 02:19 pm

‘Selfish’ genetics amplify inflammation, age-related diseases

Research from Rochester biologists shows that a class of genomic parasites may cause more harm than previously thought, triggering inflammation that causes age-related diseases.

topics: Aging, Andrei Seluanov, Department of Biology, genetics, research finding, Vera Gorbunova,
naked mole rat
Science & Technology
February 6, 2018 | 10:47 am

Why do naked mole rats live long, cancer-free lives?

Rochester biologists were surprised to see that despite its remarkable longevity, the naked mole rat still has cells that undergo senescence, like the cells in much shorter-lived mice.

topics: Aging, Andrei Seluanov, cancer, Department of Biology, featured-post-side, naked mole rat, research finding, School of Arts and Sciences, Vera Gorbunova,
kinase protein
Science & Technology
September 8, 2016 | 05:04 pm

Protein found that initiates DNA repair

Researchers who specialize in the study of aging have identified a protein that may serve as a first responder, activating a “longevity gene” known as sirtuin 6 and setting in motion a cascade of molecular first responders to repair damaged DNA.

topics: Aging, Andrei Seluanov, Department of Biology, genetics, Natural Sciences, School of Arts and Sciences, Vera Gorbunova,