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Tag: Andrei Seluanov

Gene regulation may hold clue to longer life

Gene regulation may hold clue to longer life

May 26, 2022

Rochester biologists who study the genetics of lifespan suggest new targets to combat aging and age-related diseases.

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Connecting the dots between aging, Alzheimer’s, and ‘junk DNA’

Connecting the dots between aging, Alzheimer’s, and ‘junk DNA’

March 16, 2022

Biologists Vera Gorbunova and Andrei Seluanov join colleagues at Brown and NYU in the quest to find potential targets of treatments and therapeutics for neurodegenerative diseases.

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Is ‘junk DNA’ a key to killing cancer cells?

Is ‘junk DNA’ a key to killing cancer cells?

October 20, 2021

Rochester biologists show how a selfish genetic element called retrotransposons that can cause tumors may also trigger the death of cancer cells.

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Bats offer clues to treating COVID-19

Bats offer clues to treating COVID-19

July 8, 2020

Bats carry many viruses, including the one behind COVID-19, without becoming ill. University of Rochester biologists are studying the immune system of bats to find potential ways to “mimic” that system in humans.

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‘Longevity gene’ responsible for more efficient DNA repair

‘Longevity gene’ responsible for more efficient DNA repair

April 19, 2019

Rochester researchers have uncovered more evidence that the key to the “Fountain of Youth” may reside in a gene that is found to produce more potent proteins in species with longer lifespans.

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‘Selfish’ genetics amplify inflammation, age-related diseases

‘Selfish’ genetics amplify inflammation, age-related diseases

March 14, 2019

Research from Rochester biologists shows that a class of genomic parasites may cause more harm than previously thought, triggering inflammation that causes age-related diseases.

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Why do naked mole rats live long, cancer-free lives?

Why do naked mole rats live long, cancer-free lives?

February 6, 2018

Rochester biologists were surprised to see that despite its remarkable longevity, the naked mole rat still has cells that undergo senescence, like the cells in much shorter-lived mice.

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Protein found that initiates DNA repair

Protein found that initiates DNA repair

September 8, 2016

Researchers who specialize in the study of aging have identified a protein that may serve as a first responder, activating a “longevity gene” known as sirtuin 6 and setting in motion a cascade of molecular first responders to repair damaged DNA.

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Parasitic DNA stops “jumping” when protein takes charge

Parasitic DNA stops “jumping” when protein takes charge

September 23, 2014

Biology researchers Vera Gorbunova and Andrei Seluanov report that the “jumping genes” in mice become active as the mice age when a multi-function protein stops keeping them in check in order to take on another role. A protein called Sirt6 is needed to keep the jumping genes—technically known as retrotransposons—inactive.

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Vertebrate of the Year!

Vertebrate of the Year!

December 23, 2013

“Here at the University, the naked mole rat seems like it has been the Vertebrate of the Year for several years,” said President Seligman.

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