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Funded Projects

Fall
2019

Diagnostic Probe to Grade Tissue Quality (Catherine Kuo, Michael Giacomelli and Edward Brown)

A New and More Efficient Reverse Genetics Approach for Influenza Virus (David Dean, Bradley Nilsson and Luis Martinez-Sobrido)

Integrating Flat-Panel Loudspeaker Technology on OLED Panels (Michael Heilemann and Mark Bocko)

Spring
2019

Color Day Camera Using Cholesteric Glassy Liquid Crystal Films as Circular Polarizers (Shaw Chen & Mitchell Anthamatten)

Broad spectrum mixed lineage kinase inhibition: a novel treatment for pancreatic adenocarcinoma (Harris Gelbard)

Nucleic Acid Encoding of Suppressor tRNAs (John Lueck)

Robust passive-cavity femtosecond sources (William Renninger)

Fall
2018

Hearing Restoration after Noise Damage with ERBB2/3 Activation (Patricia White)

Spring
2018

An Integrated Gene Editing Approach for the Correction of Muscular Dystrophy (Douglas Anderson)

Fiber Array to Silicon Photonic Chip Optical Packaging (Jaime Cardenas)

Pre-clinical development of a human monoclonal antibody cocktail (URnFluhmAb) for the universal prevention and treatment of influenza infection (James Kobie & Luis Martinez-Sobrido)

Development of MTTL1, a small molecule MEK inhibitor for the treatment of cancers with high MAP kinase pathway activity (Rakesh Singh & Rachael Turner)

Fall
2017

Developing EPOR small molecule inhibitors to improve engraftment in hematopoietic stem cell transplantation (Omar Aljitawi)

Macrocyclic Inhibitors of the Hedgehog Signaling Pathway (Rudi Fasan & David Linehan)

Development of a Clinically Relevant Disease Specific Patient Reported Outcome Measure for use in Drug Labeling Claims in Lung Cancer Therapeutic Trials (Chad Heatwole)

Spring
2017

In-vivo Photoacoustic & ultrasound imaging probe for human thyroid cancer detection (Vikram Dogra & John Ellis)

URMC-099 Therapy for Amyotrophic Lateral Sclerosis (Handy Gelbard)

A novel and more effective live-attenuated vaccine for the prevention and control of equine influenza virus in horses (Luis Martinez-Sobrido)

Fall
2016

Novel antibiotic formulations for the prevention and treatment of ocular infections (Paul Dunman & Rachel Wozniak)

Development of a Clinically Relevant Disease Specific Patient Reported Outcome Measure for use in Drug Labeling Claims in Crohn’s Disease Therapeutic Trials (Chad Heatwole)

VLA-3: a novel sepsis biomarker (Minsoo Kim & Anthony Pietropali)

Development of MeTC7, a small molecule inhibitor of PD-L1 for immunotherapy of ovarian cancer, breast cancer and melanoma (Rakesh Singh)

Spring
2016

Shape-memory thermoset fibers (Mitchell Anthamatten)

Preclinical testing of transepithelial vaccine delivery technology (Lisa Beck & Benjamin Miller)

Ultra-collagen for enhanced wound healing (Diane Dalecki)

Electric field treatment to prevent and treat rhinitis and asthma (David Dean & Steve Georas)

Carbon nanotube arrays for high efficiency gene transfer (Ian Dickerson)

Ultrasensitive chip-scale integrated nano-optomechanical inertial sensors (Qiang Lin)

Fall
2015

Bone-Targeted Drug Delivery (Robert Boeckman)

Macrocyclic Inhibitors of the human PGC1B CBP80 protein-protein interaction (Rudi Fasan & Lynn Maquat)

High Brightness Volumetric 3D Display (John Howell)

Live attenuated vaccines for the treatment and control of canine influenza virus (Luis Martinez-Sobrido)

Spring
2015

Further Development of Planar Loudspeakers (Mark Bocko)

A Computational Ultrasound Method for Portable High-Resolution Imaging Applications (Zeljko Ignjatovic)

Spectrally Pure, Manufacture-Ready, High-Power Semiconductor Laser (John Marciante)