Cleaning up the aging brain
Rochester scientists are restoring the brain’s trash disposal system with a drug currently used to induce labor.
AI helps show how the brain’s fluids flow
A new, AI-based technique for measuring fluid flow in the brain could lead to treatments for diseases such as Alzheimer’s.
Can the laws of physics untangle traffic jams, stock markets, and other complex systems?
Gourab Ghoshal is using the fundamental laws of physics to untangle the complex systems behind human behavior, urban planning, and social networks.
Not all sleep is equal when it comes to cleaning the brain
New research shows how the depth of sleep can impact our brain’s ability to efficiently wash away waste and toxic proteins, reinforcing the links between aging, sleep deprivation, and heightened risk for Alzheimer’s disease.
Study suggests how high blood pressure might contribute to Alzheimer’s
New Rochester research may help explain the connection between high blood pressure and Alzheimer’s disease, and it’s all to do with how the brain pumps away waste.
Grant will examine link between ‘dirty’ brains and Alzheimer’s
A $3.2 million grant from the National Institute on Aging brings together scientists from the Medical Center and engineers from the River Campus to develop a detailed understanding of the brain’s waste removal system.
Research to explore new therapies for Huntington’s disease
A new grant anticipated to total more than $10.5 million over next five years will help Medical Center scientists develop a stem cell-based therapy that swaps sick brain cells for healthy ones.
Study reveals brain’s finely tuned system of energy supply
The brain uses a “just in time” system for delivering the oxygen that fuels nerve cells. These findings from the University’s Center for Translational Neuromedicine could shed light on the cognitive decline that accompanies diseases like Alzheimer’s.
Swapping sick for healthy brain cells slows Huntington’s disease
Medical Center researchers have successfully reduced the symptoms and slowed the progression of Huntington’s disease by replacing sick mouse glia cells with healthy human cells. The findings could ultimately point to a new method to treat the disease.
Subtle chemical changes in brain can alter sleep-wake cycle
A new study by Maiken Nedergaard, co-director of the University’s Center for Translational Neuromedicine, reveals that our sleep-wake state appears to be dependent upon the concentration and balance of ions in the cerebral spinal fluid.