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Tag: Maiken Nedergaard

New grant will unlock workings of the brain’s waste removal system

New grant will unlock workings of the brain’s waste removal system

August 16, 2022

Rochester scientists discovered the glymphatic system. Now, the National Institutes of Health is bringing together several teams of researchers to better understand its mechanics.

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At age 80, John Thomas writes new chapter in an illustrious career

At age 80, John Thomas writes new chapter in an illustrious career

January 31, 2022

The Rochester professor emeritus and new American Astronomical Society fellow now explores the brain’s waste disposal system.

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Not all sleep is equal when it comes to cleaning the brain

Not all sleep is equal when it comes to cleaning the brain

February 27, 2019

New research shows how the depth of sleep can impact our brain’s ability to efficiently wash away waste and toxic proteins, reinforcing the links between aging, sleep deprivation, and heightened risk for Alzheimer’s disease.

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Study suggests how high blood pressure might contribute to Alzheimer’s

Study suggests how high blood pressure might contribute to Alzheimer’s

January 25, 2019

New Rochester research may help explain the connection between high blood pressure and Alzheimer’s disease, and it’s all to do with how the brain pumps away waste.

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Low levels of alcohol good for the brain

Low levels of alcohol good for the brain

February 2, 2018

A Medical Center shows for the first time that low levels of alcohol consumption tamp down inflammation and helps the brain clear away toxins, including those associated with Alzheimer’s disease.

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Grant will examine link between ‘dirty’ brains and Alzheimer’s

Grant will examine link between ‘dirty’ brains and Alzheimer’s

September 20, 2017

A $3.2 million grant from the National Institute on Aging brings together scientists from the Medical Center and engineers from the River Campus to develop a detailed understanding of the brain’s waste removal system.

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Study reveals brain’s finely tuned system of energy supply

Study reveals brain’s finely tuned system of energy supply

August 8, 2016

The brain uses a “just in time” system for delivering the oxygen that fuels nerve cells. These findings from the University’s Center for Translational Neuromedicine could shed light on the cognitive decline that accompanies diseases like Alzheimer’s.

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Subtle chemical changes in brain can alter sleep-wake cycle

Subtle chemical changes in brain can alter sleep-wake cycle

April 28, 2016

A new study by Maiken Nedergaard, co-director of the University’s Center for Translational Neuromedicine, reveals that our sleep-wake state appears to be dependent upon the concentration and balance of ions in the cerebral spinal fluid.

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Immune system cells key to maintaining blood-brain barrier

Immune system cells key to maintaining blood-brain barrier

January 11, 2016

New Medical Center research shows that the cells responsible for protecting the brain from infection and inflammation are also responsible for repairing the system of defenses that separates the brain from the rest of the body.

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Blows to head damage brain’s ‘garbage truck,’ accelerate dementia

Blows to head damage brain’s ‘garbage truck,’ accelerate dementia

December 2, 2014

A new study out today in the Journal of Neuroscience shows that traumatic brain injury can disrupt the function of the brain’s waste removal system. When this occurs, toxic proteins may accumulate in the brain, setting the stage for the onset of neurodegenerative diseases such as Alzheimer’s.

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